Evidence and substantiation
Laser Equipment Global publishes the sources behind its clinical and technical claims. Every claim on this site has an approved claim record naming its supporting evidence, the reviewer who approved it, and the date it must be re-verified.
How a claim gets published
- A claim is written down. Not as marketing copy — as a record, with the exact wording that may be used.
- Evidence is attached. A regulator record, a peer-reviewed study, or manufacturer documentation. A claim with nothing behind it does not proceed.
- A reviewer approves it, and is named on the record.
- The pages it may appear on are listed. A claim approved for one context does not travel to another by itself.
- An expiry date is set. On that date it is re-verified or withdrawn.
This is why some questions get routed to a specialist rather than answered on the page or by our online advisor. Where we do not hold approved evidence, we would rather say so than publish something we cannot stand behind.
The evidence library
13 sources, grouped by type. Each was retrieved and verified on the date shown.
Regulator record (1)
Peer-reviewed study (11)
- Anderson RR, Parrish JA. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science. 1983;220(4596):524–527. (PMID 6836297)
- Bäumler W, et al. Efficacy and adverse reactions of laser-assisted tattoo removal: a prospective split study using nanosecond and picosecond lasers. JEADV. 2022. (PMID 34543473)
- Feng J, Shen S, Song X, Xiang W. Efficacy and safety of picosecond laser for melasma: a systematic review and meta-analysis. Lasers Med Sci. 2023;38(1):84. (PMID 36897459)
- Hong JK, et al. Split-face study comparing 1064-nm picosecond vs Q-switched Nd:YAG laser toning for melasma. J Dermatolog Treat. 2022;33(5):2547–2553. (PMID 35067157)
- Ismail MA, et al. Removal of black tattoos by picosecond Q-switched Nd:YAG laser in Middle Eastern skin type IV. Lasers Med Sci. 2024. (PMID 39136867)
- Kono T, et al. Prospective comparison of 532/1064 nm picosecond vs nanosecond laser for professional tattoos in Asians. Laser Ther. 2020. (PMID 32903983)
- Kono T, Shek SY, Chan HHL, et al. Theoretical review of the treatment of pigmented lesions in Asian skin. Laser Ther. 2016;25(3):179–184. (PMID 27853342)
- Lee SS, et al. Noninvasive cosmetic treatments for Fitzpatrick IV–VI: a narrative review of safety and efficacy. Plast Reconstr Surg Glob Open. 2026;14(3):e7541. (PMID 41884758)
- Liang S, et al. Picosecond Nd:YAG (1064 nm) vs picosecond alexandrite (755 nm) vs 2% hydroquinone for melasma: a randomized, assessor-blinded trial. Front Med. 2023. (PMID 37056729)
- Nguyen HT, et al. Safety and efficacy of tattoo removal using a dual-wavelength 1064/532-nm picosecond laser in Fitzpatrick III–IV. Lasers Surg Med. 2021;53(7):939–945. (PMID 33027538)
- Reiter O, et al. Picosecond lasers for tattoo removal: a systematic review. Lasers Med Sci. 2016;31(7). (PMID 27311768)
Manufacturer manual (1)
- Pro 1 Pico Product Manual